Case Series


Incidental discovery of seminoma after simple orchiectomy in transgender individuals: A case series

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1 BA, BS, Medical Student, University of Utah School of Medicine, Salt Lake City, Utah, USA

2 MD, Fellow, Department of Urology, University of Utah, Salt Lake City, Utah, USA

3 MD, Assistant Professor of Pathology, Department of Pathology, University of Utah, Salt Lake City, Utah, USA

4 MD, Associate Professor of Plastic Surgery, Department of Plastic Surgery, University of Utah, Salt Lake City, Utah, USA

5 MD, MS, FECSM, Associate Professor of Urology, Department of Urology, University of Utah, Salt Lake City, Utah, USA

6 MD, Assistant Professor, Department of Urology, University of Utah, Salt Lake City, Utah, USA

Address correspondence to:

Telisha Tausinga

BA, BS, University of Utah School of Medicine, 30 N 1900 E, Salt Lake City, UT 84132,

USA

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Article ID: 100038Z15TT2023

doi: 10.5348/100038Z15TT2023CS

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How to cite this article

Tausinga T, Snyder L, Mahlow J, Agarwal C, Hotaling JM, McCormick BJ. Incidental discovery of seminoma after simple orchiectomy in transgender individuals: A case series. J Case Rep Images Urol 2023;8(2):22–29.

ABSTRACT


Introduction: Seminoma is a common malignancy reported in young, cisgender men. However, there is sparse literature describing cases of seminoma in the transgender and gender diverse patient population.

Case Series: We present two cases of seminoma incidentally discovered after simple bilateral orchiectomy performed as part of genital gender affirming surgery. In both instances, patients had not reported any testicular firmness or abnormality prior to surgery. After a thorough literature review, only two other such cases have been reported. Herein, we discuss our two cases and their implications for surgical management of suspected testicular malignancy intraoperatively, a methodical inspection of testicles removed during gender affirming surgery and providing affirming care when navigating discussions of genitalia with transgender and gender diverse patients.

Conclusion: Testicular malignancy such as seminoma may be found incidentally when transgender and gender diverse patients undergo genital gender affirming surgery. Thus, special attention is required to identify suspicious exam findings, adjust surgical techniques as indicated, and properly examine surgical specimens. As there is a significant paucity of literature surrounding testicular malignancies in the transgender and gender diverse patient population, it is crucial to continue to investigate how to provide affirming care in these situations.

Keywords: Gender-affirming surgery, Seminoma, Surgical pathology inspection, Transgender health

SUPPORTING INFORMATION


Acknowledgments

We would like to gratefully acknowledge Ana Lucia Ruano, MD for her assistance in obtaining histological slides for this case series.

Author Contributions

Telisha Tausinga - Conception of the work, Design of the work, Acquisition of data, Analysis of data, Drafting the work, Revising the work critically for important intellectual content, Final approval of the version to be published, Agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.

Liem Snyder - Conception of the work, Design of the work, Acquisition of data, Analysis of data, Revising the work critically for important intellectual content, Final approval of the version to be published, Agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.

Jonathon Mahlow - Conception of the work, Design of the work, Analysis of data, Revising the work critically for important intellectual content, Final approval of the version to be published, Agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.

Cori Agarwal - Conception of the work, Design of the work, Acquisition of data, Analysis of data, Drafting the work, Revising the work critically for important intellectual content, Final approval of the version to be published, Agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.

James M Hotaling - Conception of the work, Design of the work, Acquisition of data, Analysis of data, Drafting the work, Revising the work critically for important intellectual content, Final approval of the version to be published, Agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.

Benjamin J McCormick - Conception of the work, Design of the work, Analysis of data, Drafting the work, Revising the work critically for important intellectual content, Final approval of the version to be published, Agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.

Guaranter of Submission

The corresponding author is the guarantor of submission.

Source of Support

None

Consent Statement

Written informed consent was obtained from the patient for publication of this article.

Data Availability

All relevant data are within the paper and its Supporting Information files.

Conflict of Interest

Authors declare no conflict of interest.

Copyright

© 2023 Telisha Tausinga et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.